What Diseases Are Studied In Clinicaltrials Gov Prs Trials?

2025-08-11 00:26:02 59

4 Answers

Owen
Owen
2025-08-12 18:22:38
From what I’ve seen, PRS trials on clinicaltrials.gov often prioritize conditions where early prediction can save lives. Breast cancer studies dominate, focusing on women with high genetic risk. Alzheimer’s trials are another hotspot, aiming to delay onset through early detection. I’ve also noticed a surge in trials for metabolic syndromes like obesity, linking genetics to dietary responses.

Less talked about but equally important are trials for kidney diseases and asthma, which explore how PRS might improve treatment plans. The breadth of diseases reflects the growing belief that genetics can guide preventive care, though challenges remain in translating scores into actionable insights.
Felicity
Felicity
2025-08-13 18:04:03
PRS trials on clinicaltrials.gov mainly tackle diseases with clear genetic markers. Cardiovascular conditions, including atrial fibrillation, are top candidates. Cancer research leans heavily into hereditary cancers like melanoma. There’s also interest in psychiatric conditions such as autism, where PRS could clarify genetic contributions. These trials are reshaping how we approach disease prevention, one gene at a time.
Daniel
Daniel
2025-08-14 12:06:32
I've noticed that clinicaltrials.gov PRS (Polygenic Risk Score) trials cover a wide range of diseases, focusing primarily on genetic predispositions. Cardiovascular diseases like coronary artery disease and hypertension are common subjects, given their strong genetic links. Type 2 diabetes is another major focus, with studies aiming to predict risk and personalize prevention strategies. Cancer research, especially breast and prostate cancer, also features prominently, leveraging PRS to identify high-risk individuals early.

Neurodegenerative conditions such as Alzheimer's and Parkinson's are increasingly studied, as PRS could revolutionize early intervention. Mental health disorders like schizophrenia and bipolar disorder are also explored, though the genetic complexity makes these trials challenging. Autoimmune diseases, including rheumatoid arthritis and lupus, round out the list, with PRS helping to unravel their genetic underpinnings. These trials represent a cutting-edge fusion of genomics and preventive medicine, offering hope for more tailored healthcare solutions.
Finn
Finn
2025-08-15 00:32:33
I’m fascinated by how PRS trials on clinicaltrials.gov target diseases with both genetic and environmental influences. Heart disease studies stand out, examining how polygenic risk interacts with lifestyle factors. Diabetes research is equally compelling, particularly in identifying who might benefit most from early lifestyle changes. Cancer trials, especially for colorectal and ovarian cancers, use PRS to refine screening protocols.

Mental health is another big area, with depression and ADHD studies gaining traction. Rare genetic disorders like cystic fibrosis are also explored, though less frequently. What’s exciting is how these trials bridge genetics and real-world health outcomes, paving the way for personalized medicine. The diversity of diseases studied highlights the versatility of PRS as a tool, even if its clinical application is still evolving.
View All Answers
Scan code to download App

Related Books

Love Trials
Love Trials
One night before our engagement, Darren Finch insisted on throwing a singles party aboard a cruise ship. He made it clear I wasn't invited. But in the middle of the night, I got a call saying he'd fallen overboard. Panic overtook me. Feverish and disoriented, I stumbled to the deck and dove into the sea without a second thought. The night waters were icy, sapping the strength from my limbs. As I was pulled back onto the deck, shivering and soaked, I heard laughter ring out from the crowd. Carrie Specter, Darren's childhood sweetheart, stood above me. She gave a soft, lilting laugh. "Seeing how far you're willing to go for Darren... I can finally hand him over to you without worry." At that, Darren wrapped an arm smugly around her waist. "Carrie, you really do know me best." "I told you," she beamed, "Paula would pass your test." I let out a cold laugh, slipped the engagement ring from my finger, and flung it at his face. "No, thanks. I wish you two eternal bliss. Just don't ever drag me into your drama again."
10 Chapters
The Marriage Trials
The Marriage Trials
Taking five deep breaths I slowly turn around to come face to face with a pair of dazzling green eyes boring into me and my heart skips a beat. "Mine." Mating between werewolves is natural but a werewolf mating with humans is a matter of war. So humans were given the chance to have the opportunity to mate with a werewolf only if they qualify in inducing feelings within the werewolf. That's what they call as 'The Marriage Trials' Hazel Barnard, a twenty year old orphan who lives under the shelter of her unkind Uncle, Aunt and a despising sister has never been able to get the attention of a wolf after she turned eighteen. But what happens when King Alpha Xavier Ash chooses her to be his marriage trial, only in the wake of rejecting her later… Will she be able to win his stone cold heart or become a slave to the rule of ruthless werewolves?
8
16 Chapters
THE ALPHA TRIALS
THE ALPHA TRIALS
Five alphas want her. One prophecy will destroy her. After surviving a supernatural attack that exposes her true lineage, Ava Pierce learns she is the Moon-Blessed, the only woman in a century fated to awaken the ancient Alpha Bond—a force that can either unify the werewolf dynasties or plunge them into war. But power never comes without a price. Ava must now face the Alpha Trials, a deadly competition where five dangerously seductive alpha heirs from rival clans must fight not only each other, but the bond forming between them and her. Each alpha wants to claim her. One of them will betray her. And all of them are hiding something. In a world ruled by dominance, prophecy, and forbidden attraction, Ava must decide whether to love, lead… or destroy them all. Because if she fails the Trials, the next full moon will mark her death.
Not enough ratings
100 Chapters
The Luna Trials
The Luna Trials
Cassy has a secret, one she’s willing to leave her home and pack to keep. But when her boyfriend, Zac, becomes the Ash Mount Beta and refuses to leave with her, her plans take a turn. Torn between fighting for the man she loves and keeping her identity hidden to protect her and her mum, Cassy only has one option. Compete in the Luna Trials - a contest where the mates of the Alpha, Beta and High Guard warriors are chosen. The challenges she faces are far beyond the strategy and strength she needs to win the Trials, and leave her conflicted at every turn. Should Cassy spill her secrets to save a friend? Should she keep fighting for a man who cares more for his title? And what is this strange new pull she has towards the Alpha? But Cassy will face her biggest challenge of all when her past comes back to haunt her.
10
56 Chapters
Tears, Trials, & Trust
Tears, Trials, & Trust
Under the full moon will Alice find her other half ready to be with her or will they choose the life they have. Will this first full moon after turning eighteen just be the start of learning what she wants or who.
10
13 Chapters
The Trials of Love
The Trials of Love
The day before our wedding, my fiancé invites our family onto a cruise ship. He says he wants to test the authenticity of my feelings for him. He shoves my mother off the ship when the waves are at their choppiest. Then, he jumps into the water, too. I'm caught between a rock and a hard place. I panic, not knowing what to do. My mother had already choked on a lot of water, but she pushed me away weakly. She cried, "Save Adrian first! He can't swim!" However, after I drag Adrian Lawson onto land and go back for my mother, I find that she's already stopped breathing. Adrian watches me cry, his expression frosty. "Drop the act. Your mother was a swimmer when she was younger—how can she be dead? I can't believe you didn't save me first. "Vi is right—you don't love me enough. Our wedding is postponed. It'll happen only after you've reflected on your mistakes and I've received an apology from you and your mother." After that, he leaves while holding Vivian Sinclair's hand. He doesn't know that my mother can no longer swim after a major illness a few years back. He's shoved her to her death.
8 Chapters

Related Questions

How Reliable Is Clinicaltrials Gov Prs For Medical Research?

3 Answers2025-08-11 17:56:24
I find clinicaltrials.gov to be a highly reliable resource for tracking ongoing and completed studies. The platform is maintained by the U.S. National Library of Medicine, which lends it credibility. Researchers are required to register trials and report results, ensuring transparency. However, the reliability of the data depends on how diligently researchers adhere to reporting guidelines. Some studies might have incomplete or delayed updates, but overall, it’s a trusted source for medical professionals and patients alike. I’ve cross-referenced information from clinicaltrials.gov with published papers and found consistent data, which reinforces my confidence in its accuracy.

Are There Any COVID-19 Trials On Clinicaltrials Gov Prs?

4 Answers2025-08-11 11:41:47
As someone who keeps a close eye on medical research, especially during the pandemic, I can confirm that there are numerous COVID-19 trials listed on ClinicalTrials.gov. The platform is a treasure trove for ongoing studies, ranging from vaccine efficacy to long-term effects of the virus. For instance, trials like 'Adaptive COVID-19 Treatment Trial (ACTT)' and 'Phase 3 Study of Novavax COVID-19 Vaccine' are actively recruiting participants. These studies are crucial for understanding the virus and developing effective treatments. I’ve noticed many trials focus on vulnerable populations, such as the elderly or those with pre-existing conditions, which is a smart move. There’s also a growing number of trials exploring repurposed drugs like ivermectin and hydroxychloroquine, though results have been mixed. If you’re curious, I recommend using the search filters on ClinicalTrials.gov to narrow down trials by location, phase, or intervention type. The sheer volume of research happening right now is both impressive and reassuring.

How To Search For Cancer Trials On Clinicaltrials Gov Prs?

3 Answers2025-08-11 11:52:05
I've had to navigate clinicaltrials.gov for a family member, and it can feel overwhelming at first. The key is using the search filters effectively. Start by typing 'cancer' into the basic search bar, then narrow it down using the advanced search options. You can filter by cancer type, stage, location, and even treatments like immunotherapy or targeted therapy. I found the 'recruiting' status filter super helpful to avoid dead ends. The site lets you save searches and get email alerts for new trials, which is a lifesaver. Don't skip reading the eligibility criteria carefully - it saves time later. The 'contacts and locations' section shows where trials are happening, and some even offer travel assistance.

Can I Join Clinical Trials Through Clinicaltrials Gov Prs?

3 Answers2025-08-11 17:01:52
I’ve been curious about clinical trials myself, especially after hearing how they can offer access to cutting-edge treatments. From what I’ve gathered, ClinicalTrials.gov is a fantastic resource run by the U.S. National Library of Medicine. It lists thousands of trials worldwide, and you can search by condition, location, or treatment type. The process seems straightforward: find a trial that matches your needs, check the eligibility criteria, and contact the study coordinator listed. I’ve heard some people get accepted quickly, while others face waiting lists. It’s not a guaranteed path, but it’s worth exploring if you’re eager to contribute to medical research or access experimental therapies.

Who Publishes Clinical Trial Results On Clinicaltrials Gov Prs?

4 Answers2025-08-11 19:55:11
As someone who keeps an eye on medical research trends, I find clinicaltrials.gov to be an invaluable resource for tracking trial results. The platform is primarily used by researchers, pharmaceutical companies, and academic institutions to publish their findings. Sponsors—whether they are biotech firms, universities, or government agencies—are required to submit results for certain trials under FDA regulations. I’ve noticed that larger pharmaceutical companies like Pfizer or Roche often post results for their late-stage drug trials, while smaller biotech firms might share early-phase data. Academic medical centers, such as Johns Hopkins or Mayo Clinic, also contribute by publishing studies led by their investigators. The transparency is crucial for advancing medical knowledge, though sometimes the data can be technical and dense. Still, it’s a goldmine for anyone interested in cutting-edge treatments or research integrity.

What Are The Latest Clinical Trials Listed On Clinicaltrials Gov Prs?

3 Answers2025-08-11 00:03:35
there are some fascinating studies popping up. One that caught my attention is a Phase III trial for a new Alzheimer's treatment targeting amyloid plaques with a novel immunotherapy approach. Another interesting one is a gene therapy trial for sickle cell anemia, which could be a game-changer for patients. There's also a cutting-edge CAR-T cell therapy study for solid tumors, which is pretty exciting because it expands beyond blood cancers. I noticed a lot of activity in the mental health space too, with trials testing psychedelics like psilocybin for treatment-resistant depression. The platform updates daily, so it's worth checking back often for the newest listings.

How To Verify A Clinical Trial'S Legitimacy On Clinicaltrials Gov Prs?

4 Answers2025-08-11 18:09:01
As someone who's spent years navigating clinical research, verifying a trial's legitimacy on 'clinicaltrials.gov' requires careful attention to detail. Start by checking the trial's registration details—legitimate studies will have a unique NCT number, clear inclusion/exclusion criteria, and a well-defined protocol. Look for institutional review board (IRB) approval, which should be listed under the 'Ethics' section. Cross-reference the principal investigator’s credentials and affiliation with reputable institutions. Another red flag is vague or overly promotional language. Genuine trials focus on methodology, not hype. Scrutinize the funding sources—studies backed by NIH or well-known universities are more trustworthy. Also, check if results are posted; legitimate trials often share outcomes even if negative. Lastly, look for contact information; fraudulent studies often lack responsive points of contact. If something feels off, trust your instincts and consult a healthcare professional.

Where To Access Free Clinical Trial Data On Clinicaltrials Gov Prs?

3 Answers2025-08-11 15:14:31
I’ve been digging into clinical trials for a personal project, and 'ClinicalTrials.gov' is my go-to for free data. The website’s Protocol Registration and Results System (PRS) is where researchers upload trial details, but public access is limited. You can search for trials on the main site and view summaries, but raw PRS data isn’t freely downloadable. For deeper access, you might need to partner with institutions or use APIs if available. I’ve found some trials also share results in journals or repositories like 'PubMed Central', which can supplement the info. It’s a bit of a treasure hunt, but worth it for thorough research.
Explore and read good novels for free
Free access to a vast number of good novels on GoodNovel app. Download the books you like and read anywhere & anytime.
Read books for free on the app
SCAN CODE TO READ ON APP
DMCA.com Protection Status