How Does Mathematical Pharmacology Improve Clinical Trial Designs?

The two of them had long been crossing paths with each other in awards shows and galas and other social events, and fates seemingly decided that they’ve had enough. One encounter led to another, and unbeknownst to them, they’ll become two important pieces and a part of each other’s life. In the face of too many adversaries and challenges that will test their love and relationship, will they be able to escape unscathed? Would their love be enough to keep them together? Or will they give it up in order to protect their interest and survive in this crazy and scary world of showbiz? “Love is not easily hindered, nor restrained. It could not be stopped or contained for it is untamed.”

A forgotten bite. A fake bond. A power no wolf was meant to command. Twelve years ago, Kira watched her home burn under a blood moon. Smoke in her lungs. A mother’s scarf in her hand. And a golden-eyed boy who bit her—not to mark her, but to silence her. He told her to stay quiet. To wait. Then he left. Now, Kira is back. Not to forgive. Not to forget. But to survive. To infiltrate the pack that destroyed her people. To find the boy who abandoned her and burn his world from the inside. But things have changed. That boy is now Alpha Ronan Vale—cold, ruthless, untouchable. When Kira is captured during the sacred Pack Trial, the Council calls for her execution. Ronan claims her instead, announcing a trial mating bond that isn’t real. At least… it’s not supposed to be. As secrets unravel and an ancient power stirs in her blood, Kira discovers she’s not just an omega. She’s something the world thought extinct—a Royal Omega, born to command alphas and destroy empires. And the fake bond? It starts to feel terrifyingly real. But the past has claws. The Council has plans. And someone is still hunting her—someone who once paid a killer to make sure she never lived long enough to be chosen. The bond was a lie. Until it wasn’t.

In the depths of his island prison, the hunter yearned for liberation, until love unexpectedly found its way into his heart. But when his beloved was torn from his grasp, he plunged into a abyss of self-blame, losing himself in the shadows of despair. A decade of mourning weighs heavily upon him, pushing him to the brink of surrender. Death's embrace seems tantalizingly close, yet the bite of a werewolf binds him to a life he no longer wishes to endure. Faced with the impossible, he must heed her call and seek both cure and poison. Yet, the path he embarks upon reveals a sinister conspiracy that reaches far beyond his shattered romance. Doubts assail his unwavering resolve, leaving him torn between seeking a new purpose and surrendering to the torment of his anguish. As fate hangs in the balance, he stands at a crossroads, the weight of a life-altering choice bearing down upon his weary soul. Will he discover a renewed reason to carry on, or will he succumb to the relentless grip of his pain? In this gripping tale of love, loss, and redemption, the hunter's journey unfolds against a backdrop of treacherous secrets and unforeseen destinies. “Will you be mine Rayla?”

Hazel Thorne loses her mate to her evil twin sister on the day of her turning, and Keith Thorne's oath with the Wyoming Alpha was that the twin without a mate must be sold off to him. When Hazel runs from her buyer days later, she comes back to wolf city to find her lost mate, but she doesn't get to return. Someone betrays her. A silver dagger lands in her heart, and then she meets Raglan. The demon Prince Raglan has an offer to save her dying self. Her days are numbered and her clock ticks at a rate of knots. She has to do everything he asks, but when a forbidden romance gets her in the path of trouble, what could possibly go wrong with baby-trapping a demon Prince? Especially when this pregnancy might belong to the sexy rogue werewolf, Micah...

Right after Ethan and I announced our mating ceremony, his childhood sweetheart from the pack, Sophia, came rushing back. And she flat-out demanded I go through a "bloodline trial." "Someone like you, a wolf outcast, you're definitely up to no good. You have to pass this month-long bloodline trial before our pack will accept your mating!" With Ethan basically giving them the nod, Sophia and her pack betas put me through hell. They deliberately messed with my moonlight alchemy circle, almost tore my mind apart. The backlash from the moon energy tortured me until I almost broke. My body felt like it was being ripped to shreds. They contaminated my sacred water potions. The choking fumes nearly suffocated me. The betas were cruel and vicious. "She's just a lone wolf anyway. If she dies, no pack will back her up." Then, Sophia stole the Moon Goddess sacred artifact my grandma left me—the Moon Alchemy Cauldron. She taunted me, all cocky. "If you've got the guts, try summoning the Moon Goddess's power on the blood moon night to take it back! Otherwise, I'll use your family's crappy old cauldron as a chamber pot!" I’ve had enough. I’m so sick of these ‘trials,’ and there’s no way in hell I’m mating with Ethan.

When Bella, my mate's first love, begged for my help, claiming her mother was gravely injured, I didn't hesitate. As the pack's Luna, I grabbed my medical kit and ran. But I arrived to find her sobbing over a corpse. Bella pointed a trembling, accusing finger at me. "My mother is dead because you were too slow!" Before I could explain, she cried out to the dark woods. "Ethan, did you see? Your Luna just stood by and let my mother die!" My mate, Alpha Ethan, emerged from the shadows, his face a mask of cold fury. He snarled, declaring me unfit to be his Luna. Now, he's forcing me into a brutal trial to prove my worth. He's even broadcasting the trial, taking live bets from werewolves across the globe on whether I'll survive. But he doesn't know the truth: Bella has already rigged the trial. The moment I step inside, I'm walking into a deathtrap.