In "Final Destination: Bloodlines," Stefani Reyes, a college student living on campus, is plagued by nightmares that mirror a disaster her grandmother, Iris Campbell, endured years earlier. In 1968, while hosting the opening party for a sky-high restaurant, Iris foresaw the building's collapse, saving everyone but ultimately disrupting fate. Death, therefore, pursues not only the survivors but also their descendants. Returning home to visit Iris, who has long lived in seclusion, Stefani discovers that Death has already begun a chain reaction of reckoning for every member of her family—from her uncle Howard to her cousin Julia, and finally to her brothers Bobby and Erika. Faced with this fate, she and her family try to decipher "Death's Design," even seeking help from a familiar face, Bludworth (Tony Todd), but they discover that their options are harsh and limited. Even her sister, Charlie, attempts to circumvent death by "resurrecting from the dead," but ultimately, they both die in a train accident. The film ends with a cruel reminder that fate cannot be completely reversed.