There's a pretty clear cutoff point in the 2011 anime adaptation of 'Hunter x Hunter'. The anime ends right after the climactic events of the Chairman Election arc, which wraps up with episode 148. That final episode gives closure on Gon's quest to find Ging and the fallout from everything that happened during the Chimera Ant arc. It's a definitive stopping point for the animated story, even though the manga continues on.
What's always struck me as interesting, though, is how that endpoint feels intentionally chosen. The arc that follows in the manga, the Dark Continent Expedition, is massively complex with a ton of new characters and political maneuvering. It's almost a different genre, shifting from adventure-battles to a dense, layered thriller. The anime's conclusion on the lighter, more resolved note of the election works perfectly as a series finale, even if it leaves the larger world unexplored. I sometimes wonder if adapting the next arc would have required a completely different pacing and tone, which might have been jarring after the intensity of the Chimera Ant saga.
Honestly, stopping at 148 was probably for the best. It gives Gon's personal journey a satisfying end point, and the new manga material is so intricate that a rushed adaptation would have ruined it. I'm content rewatching up to there and just keeping up with the manga releases, whenever they decide to come out.