Sasuke never actually kills Sakura in 'Naruto' or 'Naruto Shippuden.' The confusion might come from some intense moments where their relationship hits rock bottom, like during the Five Kage Summit arc when Sasuke’s descent into darkness peaks. In episode 213 of 'Naruto Shippuden,' titled 'The Burden,' Sasuke attacks Sakura after she tries to confront him about his actions. He’s consumed by hatred and nearly strikes her down, but Kakashi intervenes just in time. It’s one of those heart-wrenching scenes that shows how far Sasuke has fallen, but Sakura survives—thankfully! Their dynamic is messy, layered, and full of unresolved tension, which makes it such a compelling part of the story.
Later, Sakura even tries to kill Sasuke herself in episode 459 ('Sakura’s Resolve'), but she can’t go through with it because of her lingering feelings. The whole thing is a rollercoaster of emotions, and honestly, it’s wild how much these two put each other through. If you’re looking for a definitive 'Sasuke kills Sakura' moment, it doesn’t exist—just a lot of near misses and emotional damage.