honestly, the term 'datura stories' has always been tricky to pin down. If we're talking about the broader folklore and the many, many books and online serials that use datura as a motif, the central figures aren't always the people who consume it. Often, it's the people affected by its poison—the bewildered victim, the terrified family member trying to piece together what happened, or sometimes the spirit of the plant itself personified.
A lot of the modern web fiction I've read, especially the horror stuff, uses it as a device to unravel a character's sanity. So the central character becomes someone losing their grip on reality, and the 'story' is the haunting, surreal vision they experience. The plant is almost a character in itself, a passive yet malevolent force. It's less about a heroic journey and more about a psychological descent, which makes picking out a traditional protagonist kind of difficult.
I remember one particular serial where the focus was split between a detective trying to solve a series of mysterious deaths and the journal of one of the victims. That dual perspective worked really well—you got the cold, procedural outside view and the terrifying, intimate inner collapse. That might be a common thread: the tension between the objective truth and the subjective, poisoned experience. So maybe the central characters are always in pairs like that, the investigator and the afflicted, the sane and the unhinged.